Publications
2014
- Luo, W., Weng, K., Yu, W., Dike, D., Liu, Y., Benham, A., Kim, J., Soibam, B., Xu, X., Cooney, A., Schwartz, R. J., Chen, L. (2014). A Molecular Switch Regulating Heart and Pancreatic Development. Circulation 130: A19676. (PDF)
2013
- Chen, L., Ma, Y., Qian, L., Wang, J. (2013). Sumoylation regulates nuclear localization and function of zinc finger transcription factor ZIC3. Biochimica et Biophysica Acta 1833: 2725–2733. (PDF)
2012
- Chen, L., Fulcoli, F. G., Ferrentino, R., Martucciello, S., Illingworth, E. A., Baldini, A. (2012). Transcriptional Control in Cardiac Progenitors: Tbx1 Interacts with the BAF Chromatin Remodeling Complex and Regulates Wnt5a. PLoS Genetics 8(3): e1002571. (PDF)
- Chen, L., Ma, Y., Kim, E. Y., Yu, W., Schwartz, R. J., Qian, L., Wang, J. (2012). Conditional Ablation of Ezh2 in Murine Hearts Reveal Its Essential Roles in Endocardial Cushion Formation, Cardiomyocyte Proliferation and Survival. PLoS ONE 7(2): e31005. (PDF)
2011
- Kim, E. Y., Chen, L., Ma, Y., Yu, W., Chang, J., Moskowitz, I. P., Wang, J. (2011). Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J. Mol. Cell. Cardiol. (PDF)
- Kim, E. Y., Chen, L., Ma, Y., Yu, W., Chang, J., Moskowitz, I. P., Wang, J. (2011). Expression of Sumoylation Deficient Nkx2.5 Mutant in Nkx2.5 Haploinsufficient Mice Leads to Congenital Heart Defects. PLoS ONE 6(6): e20803. (PDF)
- Wang, J., Chen, L., Wen, S., Zhu, H., Yu, W., Moskowitz, I. P., Shaw, G. M., Finnell, R. H., Schwartz, R. J. (2011). Defective Sumoylation Pathway Directs Congenital Heart Disease. Birth Defects Research (Part A) 9: 468–476. (PDF)
- Chen, Y., Li, Y., Chen, L., Yang, X., Su, P., Cai, J. (2011). The infarcted cardiac microenvironment cannot selectively promote embryonic stem cell differentiation into cardiomyocytes. Cardivascular Pathology 20: 77–83. (PDF)
2010
- Chen, L., Mupo, A., Huynh, T., Cioffi, S., Woods, M., Jin, C., McKeehan, W., Thompson-Snipes, L., Baldini, A., Illingworth, E. (2010). Tbx1 regulates Vgfr3 and is required for lymphatic vessel development. J. Cell Biology 189(3): 417–424. (PDF)
2009
- Chen, L., Fulcoli, F. G., Tang, S., Baldini, A. (2009). Tbx1 Regulates Proliferation and Differentiation of Multipotent Heart Progenitors. Circulation Research 105: 842–851. (PDF).
2007
- Huynh, T., Chen, L., Terrell, P., Baldini, A. (2007). A Fate Map of Tbx1 Expressing Cells Reveals Heterogeneity in the Second Cardiac Field. Genesis 45: 470–475. (PDF).