Publications

2014

Luo, W., Weng, K., Yu, W., Dike, D., Liu, Y., Benham, A., Kim, J., Soibam, B., Xu, X., Cooney, A., Schwartz, R. J., Chen, L. (2014). A Molecular Switch Regulating Heart and Pancreatic Development. Circulation 130: A19676. (PDF)

Chen, L., Ma, Y., Qian, L., Wang, J. (2013). Sumoylation regulates nuclear localization and function of zinc finger transcription factor ZIC3. Biochimica et Biophysica Acta 1833: 2725–2733. (PDF)

Chen, L., Fulcoli, F. G., Ferrentino, R., Martucciello, S., Illingworth, E. A., Baldini, A. (2012). Transcriptional Control in Cardiac Progenitors: Tbx1 Interacts with the BAF Chromatin Remodeling Complex and Regulates Wnt5a. PLoS Genetics 8(3): e1002571. (PDF)
Chen, L., Ma, Y., Kim, E. Y., Yu, W., Schwartz, R. J., Qian, L., Wang, J. (2012). Conditional Ablation of Ezh2 in Murine Hearts Reveal Its Essential Roles in Endocardial Cushion Formation, Cardiomyocyte Proliferation and Survival. PLoS ONE 7(2): e31005. (PDF)

Kim, E. Y., Chen, L., Ma, Y., Yu, W., Chang, J., Moskowitz, I. P., Wang, J. (2011). Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J. Mol. Cell. Cardiol. (PDF)
Kim, E. Y., Chen, L., Ma, Y., Yu, W., Chang, J., Moskowitz, I. P., Wang, J. (2011). Expression of Sumoylation Deficient Nkx2.5 Mutant in Nkx2.5 Haploinsufficient Mice Leads to Congenital Heart Defects. PLoS ONE 6(6): e20803. (PDF)
Wang, J., Chen, L., Wen, S., Zhu, H., Yu, W., Moskowitz, I. P., Shaw, G. M., Finnell, R. H., Schwartz, R. J. (2011). Defective Sumoylation Pathway Directs Congenital Heart Disease. Birth Defects Research (Part A) 9: 468–476. (PDF)
Chen, Y., Li, Y., Chen, L., Yang, X., Su, P., Cai, J. (2011). The infarcted cardiac microenvironment cannot selectively promote embryonic stem cell differentiation into cardiomyocytes. Cardivascular Pathology 20: 77–83. (PDF)

Chen, L., Mupo, A., Huynh, T., Cioffi, S., Woods, M., Jin, C., McKeehan, W., Thompson-Snipes, L., Baldini, A., Illingworth, E. (2010). Tbx1 regulates Vgfr3 and is required for lymphatic vessel development. J. Cell Biology 189(3): 417–424. (PDF)

Chen, L., Fulcoli, F. G., Tang, S., Baldini, A. (2009). Tbx1 Regulates Proliferation and Differentiation of Multipotent Heart Progenitors. Circulation Research 105: 842–851. (PDF).

Huynh, T., Chen, L., Terrell, P., Baldini, A. (2007). A Fate Map of Tbx1 Expressing Cells Reveals Heterogeneity in the Second Cardiac Field. Genesis 45: 470–475. (PDF).